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目的:探讨血磷浓度与脓毒症患者疾病严重程度及预后的相关性。方法:选择2012-06-2014-05我院重症医学科共收治脓毒症患者147例,选取其中存在低磷血症的62例(血磷浓度≤0.8mmol/L)患者做回顾性研究,并根据血磷水平分为2组,A组:低中度低磷组(血磷浓度0.8~0.30mmol/L);B组:重度低磷组(血磷浓度<0.30mmol/L),比较2组患者APACHEⅡ评分及病死率,同时根据预后分为存活组及死亡组,比较2组性别、血磷浓度、年龄、降钙素原(PCT)等因素。结果:A、B 2组APACHEⅡ评分及病死率比较差异有统计学意义(P<0.05);死亡组血磷明显低于存活组(P<0.05),而存活组与死亡组年龄、性别比较差异无统计学意义,死亡组降钙素原高于存活组(P<0.05)。结论:脓毒症患者血磷浓度越低,病情越重,预后越差。血磷水平可作为判断脓毒症患者预后的指标之一。
Objective: To investigate the relationship between the serum phosphorus level and the severity and prognosis of patients with sepsis. Methods: A total of 147 patients with sepsis were admitted to the Department of Critical Care Medicine of our hospital from June 2012 to June 2014. Sixty-two patients with hypophosphatemia (serum phosphorus ≤0.8mmol / L) were selected for retrospective study. According to the level of serum phosphorus, the patients were divided into two groups: group A: low and medium low phosphorus group (serum phosphorus concentration 0.8-0.30mmol / L); group B: severe low phosphorus group (serum phosphorus concentration <0.30mmol / L) The APACHEⅡscore and mortality were compared between the two groups according to the prognosis. The gender, serum phosphorus, age, procalcitonin (PCT) and other factors were compared between the two groups. Results: There was significant difference in APACHEⅡscore and mortality among group A and group B (P <0.05). The serum phosphorus in death group was significantly lower than that in survival group (P <0.05), while the difference between survival group and death group was significant No statistical significance, death group of procalcitonin than survivors (P <0.05). Conclusion: The lower serum phosphorus concentration in sepsis patients, the more severe the disease, the worse the prognosis. Serum phosphorus levels can be used as a prognostic indicator of sepsis.