The aim of this study is to shed light on the hydrogeochemical characteristics of karst underground waters at shallow depth in Guiyang City, Guizhou Province with an emphasis on the geochemistry of major elements. Guiyang City bears abundant underground waters and it is also an important representative of the karst areas throughout the world. Ca 2+ and Mg 2+ are the dominant cations, accounting for 81%- 99.7% of the total, and HCO -3 and SO 2- 4 are the dominant anions. Weathering of limestones and dolostones is the most important factor controlling the hydrogeochemistry of underground waters, and weathering of sulfate and evaporite rocks is less important. Moreover, the precipitation and human activities also have a definite influence on the hydrogeochemistry of underground waters in the region studied.