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目的：研究电刀能量的改变对喉返神经的影响，探讨使用电刀的安全能量范围。方法选择实验用猪12只，设定电刀头与神经的距离为1 mm，作用时间为3 s，按照电刀的功率（45 W、90 W、135 W）分成3组。用喉返神经监测仪测量实验前后喉肌电图的数值，并进行统计分析。并取神经组织制作病理切片，观察损伤前后的组织学变化。结果实验组2和实验组3振幅与术前比较差异有统计学意义（P ＜0．05），与实验组1比较，差异无统计学意义。组织学检查显示实验组3有明显变化。结论电刀在喉返神经周围使用的安全能量范围是功率小于90 W。“,”Objective To study the influence of energy level of electric knife on the recurrent la-ryngeal nerve in a porcine animal model and discuss the safe energy range of high-frequency electric knife in surgical operation.Methods The experiment was set up in 12 pigs.The distance from the head of elec-tric knife to the nerve was one millimeter and the action time was three seconds.The animals were random-ly divided into three groups according to the energy level(45 W,90 W,and 135 W).Preoperative and postoperative electromyogram of laryngeal muscle were recorded and analyzed by a laryngeal nerve detec-tor.Nerve tissues were extracted to make pathological sections for histological observation.Results The nerve detector indicated that the difference in amplitude between group 2(90 W)and group 3(135 W)was significant(P <0.05).No significant difference was observed in group 1(45 W).Histological study shows that obvious injury in group 3(135 W).Conclusion In thyroid surgery,the safe energy range of electric knife for recurrent laryngeal nerve should be less than 90 W.