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米非司酮(mifepristone,RU486)是一种高效抗孕激素药物,临床上广泛应用于抗早孕、紧急避孕、子宫肌瘤和子宫内膜异位症等。体外实验发现,米非司酮可抑制子宫内膜癌细胞生长及其他肿瘤。本研究将米非司酮应用于子宫内膜增生治疗,现报道如下。
Mifepristone (RU486) is a highly effective antiprogestin, which is widely used clinically in early pregnancy, emergency contraception, uterine fibroids and endometriosis. In vitro experiments found that mifepristone can inhibit the growth of endometrial cancer cells and other tumors. In this study, mifepristone used in endometrial hyperplasia, are reported below.