牙齿外源性黑色素沉着(black extrinsic tooth stain)是牙齿变色中的常见类型。这种黑色素紧密地粘附在牙齿表面,很难通过刷牙去除[1],既影响美观,也容易被患者误认为龋,长期困扰着很多人。本文将从以下五个方面总结牙齿外源性黑色素沉着的研究进展:定义、流行病学调查结果、成分、形成的影响因素及治疗。一、定义色素沉着可分为内源性与外源性。外源性色素沉着是由外源性色素附着于牙齿表面引起的,包括 Dark extrinsic tooth stain is a common type of tooth discoloration. This melanin closely adhered to the tooth surface, it is difficult to remove by brushing [1], both affect the appearance, but also easily mistaken for caries patients, long plagued many people. This article will summarize the research progress of exogenous melanopsin from the following five aspects: definition, epidemiological survey results, composition, the formation of the influencing factors and treatment. First, the definition of pigmentation can be divided into endogenous and exogenous. Exogenous pigmentation is caused by the attachment of exogenous pigments to the tooth surface, including