分别通过静脉和呼吸道急性镉染毒，探讨了急性镉中毒大鼠致死时，血液、心、肝、肾、脑、肺的镉分布。80只Wistar大鼠分为对照组和染毒组，氯化镉进行急性染毒，在心肌收缩功能降低为染毒前的50％及心跳停止时，取器官标本，用原子吸收分光光度计测定镉含量。实验结果提示，急性镉中毒时，血液、心脏的镉含量早期升高缓慢，后期升高较快，肝脏镉含量呈线性快速升高；而肾脏镉含量经呼吸道染毒时与肝脏类似，经静脉染毒时，早期升高较快，后期升高缓慢。两种染毒方法致死时，血液、心、肝、肾、脑的镉含量基本一致，这些组织和器官有一稳定的镉致死临界值。 The cadmium distribution in blood, heart, liver, kidney, brain and lung was investigated through acute cadmium exposure in veins and respiratory tract. Eighty Wistar rats were divided into control group and exposure group. Cadmium chloride was used for acute exposure. When myocardial contractile function was reduced to 50% before exposure and cardiac arrest, organ samples were taken and determined by atomic absorption spectrophotometer Cadmium content. The experimental results suggest that acute cadmium poisoning, the blood and heart of cadmium content increased slowly early, rapid increase late, the liver rapidly increased linearly with cadmium; and kidney cadmium content by the respiratory tract when exposed to the liver and similar, through the vein When exposed to the virus, the early increase is rapid and the late increase is slow. The two methods of exposure to death, the blood, heart, liver, kidney and brain cadmium content is basically the same, these tissues and organs have a stable critical value of lethality of cadmium.