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目的分析1304例呼吸道感染患者病原体检测情况,为本地区呼吸道感染病原体流行病学提供资料。方法采用间接免疫荧光法(IFA)对1304例呼吸道感染患者血液中嗜肺军团菌(LP)、肺炎支原体(MP)、Q热立克次体(COX)、肺炎衣原体(CP)、呼吸道合胞病毒(RSV)、腺病毒(ADV)、甲型流感病毒(IFA)、乙型流感病毒(IFB)、副流感病毒(PIVs)等九项病原体进行检测,分析各种病原体的检出情况。结果 1304例患者中,九项病原体检测阳性率为72.09%(940/1304),单项病原体检出率为55.29%(721/1304),依次为MP 33.01%(238/721),IFB 26.07%(188/721),LP 18.31%(132/721),PIVs 12.34%(89/721),RSV 6.24%(45/721),ADV 1.39%(10/721),CP 1.25%(9/721),COX 0.97%(7/721),IFA 0.42%(3/721);混合感染检出率为16.79%(219/1304);LP、MP、IFB在不同季节检出率有明显差别。结论本地区呼吸道感染病原体检出率较高,以MP、IFB、LP、PIVs感染为主,应及早进行不同病原体免疫球蛋白(Ig M)检测,给临床提供准确的检验信息。
Objective To analyze the pathogen detection in 1304 cases of respiratory tract infection and provide information for the epidemiology of respiratory tract infection in this area. Methods The blood samples of 1304 patients with respiratory tract infection were analyzed by indirect immunofluorescence assay (IFA). The levels of LP, MP, COX, CP, respiratory syncytial Nine pathogens such as RSV, ADV, IFA, IFB and PIVs were detected and the detection of various pathogens was analyzed. Results Among the 1304 patients, the positive rate of nine pathogens was 72.09% (940/1304), the detection rate of single pathogens was 55.29% (721/1304), followed by MP 33.01% (238/721), IFB 26.07% 188/721), LP 18.31% (132/721), PIVs 12.34% (89/721), RSV 6.24% (45/721), ADV 1.39% (10/721), CP 1.25% (9/721) COX 0.97% (7/721) and IFA 0.42% (3/721). The detection rate of mixed infection was 16.79% (219/1304). The detection rates of LP, MP and IFB were significantly different in different seasons. Conclusions The prevalence of respiratory tract pathogens in this area is high. The infection with MP, IFB, LP and PIVs is the major cause. The detection of IgM in different pathogens should be carried out as soon as possible to provide accurate clinical information.