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目的:观察胰岛素对急性脑血管病的疗效。方法:对423例脑梗死、脑出血病人,在常规治疗的基础上加用胰岛素16-20u,qd×10-14。并与常规治疗的309例作对比研究。以改良爱丁堡斯堪的纳维亚评分为评价标准。结果:治疗组与对照组脑梗死病人总效率分别为85.14％(252/296)和73.1％(150/205),(P<0.005),治疗组脑出血病人的总体疗效亦明显优于对照组;两组脑梗死病人的治愈率分别为15.54％(46/296)和11.71％(24/205),脑出血病人为22.05％(28/127)12.5％(13/104)(P<0.05);显著进步率分别为41.89％(124/296)和25.37％(52/205),34.65％(44/127)和17.31％(18/104),(P<0.05)。治疗组与对照组脑梗死病人神经功能开始恢复的时间分别为发病后9.17±2.14和13.84±2.51天,脑出血为14.83±2.44和21.06±3.82天,(P<0.05)。结论:胰岛素对急性脑血管病有一定疗效,可提高存活者的生存质量,胰岛素可作为急性脑血管病的辅助治疗手段。
Objective: To observe the effect of insulin on acute cerebrovascular disease. Methods: 423 cases of cerebral infarction, cerebral hemorrhage patients, in the conventional treatment based on the use of insulin 16-20u, qd × 10-14. And compared with conventional treatment of 309 cases. To improve the Scandinavian score of Edinburgh as the evaluation criteria. Results: The total effective rate of cerebral infarction in treatment group and control group were 85.14% (252/296) and 73.1% (150/205) respectively (P <0.005), and the overall curative effect of treatment group was better than that of control group ; The cure rates of two groups of patients with cerebral infarction were 15.54% (46/296) and 11.71% (24/205) respectively, and those with cerebral hemorrhage were 22.05% (28/127) 12.5% (13/104) (P <0.05) ; Significant improvement rates were 41.89% (124/296) and 25.37% (52/205), 34.65% (44/127) and 17.31% (18/104) respectively (P <0.05). The recovery time of neurological function of the patients in the treatment group and the control group was 9.17 ± 2.14 and 13.84 ± 2.51 days after onset and 14.83 ± 2.44 and 21.06 ± 3.82 days after the onset of cerebral infarction (P <0.05). Conclusion: Insulin has a certain effect on acute cerebrovascular disease, which can improve the quality of life of survivors. Insulin can be used as an adjunctive treatment for acute cerebrovascular disease.