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由我国卫生部和世界卫生组织派出的《动脉粥样硬化和冠心病考察组》于1983年10月22日至11月13日赴美考察。参观了6个城市的10个医学中心,现将该国一些研究近况简要介绍于下。一、冠心病流行病学和预防美国是冠心病高发病国家,全国共有冠心病患者约400万,每年约有70万心肌梗塞发作。1949年开始了Framingham地区冠心病流行病学研究,研究出吸烟、高血压、高血脂、超体重、缺少运动、糖尿病、阳性家族史等为主要的易患因素。研究对象目前尚有60％存活。10年前又开始对第二代对象进行研究。1965年开始了檀香山心脏研究规划,发现旧金山日本人冠心病死亡率高于日本本土者10倍,而在夏威夷者则介于两者之间,西方饮食方式为日本人患冠心病的正相关因素,适量饮酒为负相关因素。目前在进行临床遗传联系、社会和环境联系的流行病学研究。进行过一些冠心病的预防性治疗试验(干预试验),其中得到阳性结果的只有急性
The study group “Atherosclerosis and Coronary Heart Disease” dispatched by China’s Ministry of Health and World Health Organization visited the United States from October 22 to November 13, Visited 10 medical centers in 6 cities and now briefly introduces some recent developments in the country. First, the epidemiology and prevention of coronary heart disease The United States is a high incidence of coronary heart disease countries, a total of about 4 million patients with coronary heart disease, about 700,000 myocardial infarction attacks each year. The Epidemiology of Coronary Heart Disease in Framingham began in 1949 and smoking, high blood pressure, hyperlipidemia, overweight, lack of exercise, diabetes, and a positive family history were the major predisposing factors. At present, 60% of the subjects survived. 10 years ago began to study the second generation of objects. The Honolulu Cardiac Research Program was started in 1965 and found that the death rate of coronary heart disease was 10 times higher in Japanese in San Francisco than in Japan and in Hawaii was between the two. The Western diet was positively correlated with coronary heart disease in Japan , Moderate amount of drinking negatively correlated. Epidemiological studies are currently underway on clinical genetic links, social and environmental links. Some preventive trials of coronary heart disease (intervention trials) have been conducted, of which the only positive result is acute