介绍了催化不对称催化反应中的一个新概念一不对称活化(asymmetric activation)及其研究的最新进展。运用不对称活化策略,一个光学活性的或者甚至外消旋的催化剂可以被另一种手性活化剂(chiral activator)选择性地活化,从而催化反应生成非外消旋产物。该方法较不对称去活化(asymmetric deactivation)方法的优点是被活化的催化剂能够产生较使用光学纯催化剂更高对映体过量的产物。 A new concept of asymmetric activation in asymmetric catalysis and its latest progress are introduced. Using an asymmetric activation strategy, an optically active or even racemized catalyst can be selectively activated by another chiral activator to catalyze the reaction to produce non-racemic products. The advantage of this method over the asymmetric deactivation process is that the activated catalyst is capable of producing a product with a higher enantiomeric excess than an optically pure catalyst.