性激素依赖在某些类型的癌症中很常见,尤其是男性前列腺癌和女性乳腺癌。多年以来,在女性乳腺癌手术后,对其施用他莫西芬药物已经成为标准的治疗方法。这种疾病依赖的是雌激素,而他莫西芬可对雌激素受体产生拮抗。然而,他莫西芬并不是纯粹的拮抗剂。同时,尽管没有确切的结论,但长期研究表明他莫西芬的效果持续不超过5年。仅在1年前完成的两个补充试验倾向于支持这 Sex hormone dependence is common in certain types of cancers, especially male and female breast cancers. Over the years, the introduction of tamoxifen has become the standard treatment for women after breast cancer surgery. The disease relies on estrogen, and tamoxifen can antagonize the estrogen receptor. However, tamoxifen is not a pure antagonist. In the meantime, despite the absence of definitive conclusions, long-term studies have shown that tamoxifen lasts for less than five years. Two complementary trials that were completed just one year ago tended to support this