趋化因子(chemokine)是一类相对分子质量(Mr)小、结构相似、具有趋化作用的细胞因子,可通过与7次跨膜的G蛋白偶联受体结合诱导多种白细胞的定向迁移。趋化因子的一级结构各不相同,通常依据氨基末端的保守半胱氨酸残基的数目和位置将它们分为4类,即:CXC、CC、XC和CX3C。此外,根? Chemokines are a class of cytokines with relatively small molecular mass (Mr), similar structure and chemotactic effect. They induce the directional migration of various leukocytes by binding with seven transmembrane G protein-coupled receptors . Chemokines have different primary structures, and they are generally classified into four groups based on the number and position of amino-terminal conserved cysteine ​​residues: CXC, CC, XC, and CX3C. In addition, root?