人类许多传染病的研究进展在一定程度上依赖于动物模型的建立,乙型肝炎(HB)也不例外。尽管HB许多临床特征来源于自然或实验性感染的患者,但要进行深入的研究,没有实验动物模型是不可能的。长期以来,人们一直希望能找到对乙型肝炎病毒(HBV)易感且经济的实验动物,并进行了多方面的研究,近年来已取得不少进展。现将国内外有关的研究现状综述如下。 The progress of many infectious diseases in humans depends to some extent on the establishment of animal models. Hepatitis B (HB) is no exception. Although many of the clinical features of HB come from patients with natural or experimental infections, it is not possible to conduct an in-depth study without experimental animal models. For a long time, people have been hoping to find experimental animals susceptible to and susceptible to Hepatitis B virus (HBV). They have conducted various researches and made some progress in recent years. Now the relevant research at home and abroad are summarized below.