论文部分内容阅读
宿主与真菌之间的粘附是宿主抗真菌免疫的起始,随后通过Toll样受体对真菌的识别及信号传导,启动非特异性和特异性免疫应答。免疫反应在抗角膜真菌感染中发挥重要作用,但其机制仍不清楚。本文就抗全身及角膜真菌感染的免疫过程和机制研究进展作一综述,以期为研究真菌性角膜炎发病机制及抗角膜真菌感染提供借鉴。
The adhesion between the host and the fungus is the initiation of host antifungal immunity, followed by the nonspecific and specific immune response initiated by recognition and signaling of the Toll-like receptor to the fungus. Immune response plays an important role in anti-corneal fungal infection, but the mechanism remains unclear. This review summarizes the progress in the immunological processes and mechanisms against systemic and corneal fungal infections in order to provide a reference for studying the pathogenesis of fungal keratitis and anti-fungal infection of the cornea.