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目的探讨ICU治疗重症急性胰腺炎(SAP)的效果。方法选取本院2010年1月~2014年5月收治的109例SAP患者作为研究对象,随机分为对照组(55例)和研究组(54例)。对照组给予常规内科治疗,研究组在对照组的基础上给予ICU综合治疗,比较两组的住院时间、死亡率及并发症发生率、APACHEⅡ评分及MODS评分、治疗72 h后各项生化指标。结果研究组的死亡率及并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。研究组治疗后的APACHEⅡ评分及MODS评分均显著低于对照组,差异有统计学意义(P<0.05)。研究组治疗后72 h的BUN、SCr、TBi L、ALT水平显著低于对照组,差异有统计学意义(P<0.05)。结论 ICU综合治疗SAP效果显著,能够有效降低死亡率及并发症发生率,改善患者的预后及生活质量,值得临床推广应用。
Objective To investigate the effect of ICU in the treatment of severe acute pancreatitis (SAP). Methods A total of 109 SAP patients admitted from January 2010 to May 2014 in our hospital were randomly divided into control group (55 cases) and study group (54 cases). The control group was given conventional medical treatment. The study group was given ICU comprehensive treatment on the basis of the control group. The hospitalization time, mortality and complication incidence rate, APACHEⅡscore and MODS score were compared between the two groups. The biochemical indexes after 72h treatment were compared. Results The mortality and complication rates in the study group were significantly lower than those in the control group (P <0.05). APACHE Ⅱ score and MODS score of the study group after treatment were significantly lower than the control group, the difference was statistically significant (P <0.05). The levels of BUN, SCr, TBi L and ALT in study group at 72 h after treatment were significantly lower than those in control group (P <0.05). Conclusion ICU comprehensive treatment of SAP significant effect, can effectively reduce the mortality and complication rate, improve patient prognosis and quality of life, it is worth to clinical application.