论文部分内容阅读
本文应用多聚酶链反应（ＰＣＲ）技术检测了６９例乙型肝炎患者（其中慢性迁延性肝炎１７例，慢性活动性肝炎２３例，肝炎后肝硬化１２例，重症乙肝１７例）外周血单个核细胞（ＰＢＭＣ）中的ＨＢＶＤＮＡ存在状态。结果显示，ＰＢＭＣ中ＨＢＶ－ＤＮＡ总阳性率为４６％，而各型乙肝间ＰＢＭＣ中ＨＢＶＤＮＡ阳性率差异无显著性（Ｐ＞０．０５），提示ＨＢＶ对ＰＢＭＣ的感染，似与乙型肝炎的临床类型无明显的相关性。
In this study, 69 cases of hepatitis B patients (17 cases of chronic persistent hepatitis, 23 cases of chronic active hepatitis, 12 cases of posthepatitis cirrhosis, 17 cases of severe hepatitis B) peripheral blood mononuclear cells (PBMCs) were detected by polymerase chain reaction (PCR) (PBMCs) in the presence of HBVDNA. The results showed that the overall positive rate of HBV-DNA in PBMC was 46%, while there was no significant difference in the positive rate of HBVDNA in PBMC among various types of hepatitis B (P> 0.05), suggesting HBV infection of PBMC was similar to that of hepatitis B There was no obvious correlation between clinical types.