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MRSA的耐药机制:是该细菌产生一种青霉素结合蛋白PBP2a(或PBP2’),与β内酰胺类抗生素亲和力减低,而产生耐药性。该PBP2a由mec A基因编码,每一种MRSA菌株都有mec A基因,而敏感株则没有,mec R1及mec I是控制基因,
MRSA resistance mechanism: the bacteria produce a penicillin-binding protein PBP2a (or PBP2 ’), with the beta-lactam antibiotics reduced affinity, resulting in resistance. The PBP2a is encoded by the mec A gene, each of the MRSA strains has the mec A gene, whereas the sensitive ones do not, mec R1 and mec I are control genes,