甘露醇注射液为常用渗透性脱水剂和利尿剂。收载于《中国药典》1995年版,其含量测定为碘量滴定法。因滴定法比较繁琐,我院试采用旋光法检测半成品。旋光法测定甘露醇需要添加络合剂,以增大甘露醇的旋光度。英国药典1973年版用硼砂;美国药典第19版和日本药局方第9版用钼酸铵。笔 Mannitol injection for the commonly used osmotic dehydration agent and diuretic. Contained in the “Chinese Pharmacopoeia” 1995 edition, its content was determined by iodometric titration. Due to more cumbersome titration, our hospital test using optical rotation method of semi-finished products. Polarimetry determination of mannitol need to add complexing agent to increase the rotation of mannitol. Bristol with British Pharmacopoeia 1973; Ammonium Molybdate with the 19th edition of the United States Pharmacopeia and the 9th edition of the Japanese Pharmacopoeia. pen