目的:评价化瘀宁坤液灌肠加药渣外敷治疗慢性盆腔炎的疗效。方法:将符合纳入标准的北京市中西医结合医院妇产科2018年1月-2019年12月收治的106例慢性盆腔炎患者采用随机数字表法分为2组，每组53例。对照组采用西医常规疗法治疗，观察组在对照组基础上联合化瘀宁坤液灌肠加药渣外敷治疗。分别于治疗前后进行中医症状评分，采用生活质量综合评定量表(Generic Quality of Life Inventory-74, GQOLI-74)评价患者生活质量，采用ELISA法检测血清CRP、TNF-α水平；记录不良反应，评价临床疗效。结果:观察组总有效率为96.2%(51/53)、对照组为83.0%(44/53)，2组比较差异有统计学意义(n χ2=4.970，n P=0.026)。治疗后，观察组中医症状评分低于对照组(n t=8.205，n P<0.01)；躯体功能、心理功能、物质生活、社会功能评分高于对照组(n t值分别为7.503、8.786、7.798、9.353，n P值均<0.001)；血清CRP[(4.52±3.46)g/L比(8.23±3.35)g/L，n t=5.608]、TNF-α[(1.00±0.35)μg/L比(1.52±0.28)μg/L，n t=14.551]水平低于对照组(n P<0.01)。n 结论:在西医常规治疗基础上联合化瘀宁坤液灌肠及药渣外敷可有效改善慢性盆腔炎患者的临床症状，降低炎性细胞因子水平，提高临床疗效。“,”Objective:To explore the clinical effect of n Huayu-Ningkun liquid enema and external application of dreg for treating chronic pelvic inflammatory disease.n Methods:A total of 106 patients with chronic pelvic inflammatory disease who met the inclusion criteria in the gynecological outpatient department of Beijing Hospital of Integrated Chinese and Western Medicine from January 2018 to December 2019 were divided into 2 groups by random number table method, with 53 patients in each group. The control group was treated with conventional western medicine therapy, and the observation group was combined with n Huayu-Ningkun liquid enema and external application of drug residue on the basis of the control group. TCM symptom scores were performed before and after treatment, and the Quality of Life of patients was evaluated by Generic Quality of Life Inventory-74 (GQOLI-74). Serum CRP and TNF-α levels were detected by ELISA, and adverse reactions during treatment were recorded.n Results:The total effective rate was 96.2% (51/53) in the observation group and 83.0% (44/53) in the control group, and the difference between the two groups was statistically significant (n χ2=4.970, n P=0.026). After treatment, the TCM symptom scores of the observation group was significantly lower than that of the control group (n t=8.205, n P<0.01). The scores of physical function, mental function, material life and social function were significantly higher than those in the control group (n t value were 7.503, 8.786, 7.798, 9.353, all n Ps<0.001). After treatment, the levels of serum CRP (4.52 ± 3.46 g/Ln vs. 8.23 ± 3.35 g/L, n t=5.608) and TNF-α (1.00 ± 0.35 μg/Ln vs. 1.52 ± 0.28 μg/L, n t=14.551) in the observation group were significantly lower than those in the control group (n P<0.01).n Conclusion:The n Huayu-Ningkun liquid enema and drug residue external application combined with western medicine can relieve the symptoms, reduce the level of inflammatory cytokines, improve clinical efficacy of the patients with chronic pelvic inflammatory disease.n