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【目的】探讨宫腔镜子宫内膜切除术(TCRE)治疗功能失调性子宫出血(dysfunctional uterine bleeding,DUB)的疗效。【方法】选取80例 DUB 患者作为研究对象,根据患者治疗方式分为两组:观察组40例,采用宫腔镜子宫内膜切除手术;对照组40例,采用非手术治疗。比较两组患者的临床疗效,分析观察组预后影响因素。【结果】观察组有效率为92.50%(37/40),显著高于对照组75.00%(30/40),其差异有统计学意义(P <0.05)。观察组患者的年龄、子宫内膜厚度、宫腔深度和子宫腺肌病与患者的预后明显相关(P <0.05)。【结论】TCRE 治疗 DUB 的临床疗效满意,患者预后与患者的年龄、宫腔深度、子宫内膜厚度和子宫腺肌病相关。“,”Objective]To study the effect of transcervical resection of endometrium(TCRE)in the treat-ment of dysfunctional uterine bleeding (DUB)and to analyze its influential factors.[Methods]80 patients were chosen as study objects,and all of the patients were divided into 2 groups:40 patients in the study group,who were treated with transcervical resection of endometrium(TCRE);40 patients in the control group,who were treated with non-surgery .The effectiveness of two groups were compared and the prognostic factors in the study group were analyzed.[Results]The effect rate of the study group was 92.50%(37/40),that of the con-trol group was 75.00% (30/40 ),the difference had statistical difference(P < 0.05 ).The prognosis of the study group was significantly related to the age,endometrial thickness,depth of uterine cavity and adenomyo-sis (P <0.05).[Conclusion]TCRE is effective enough in the treatment of DUB,and the prognosis of pa-tients is related to the age,endometrial thickness,depth of uterine cavity and adenomyosis.