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2016年春季山西部分种猪场乳猪暴发腹泻,通过在山西太原、祁县、介休、昔阳、临汾、翼城、离石、朔州8个地市的10个临床表现腹泻症状的规模化种猪场进行调研,对乳猪病死情况进行了统计分析,并采集39份病死猪的小肠内容物进行猪流行性腹泻病毒(PEDV)、猪传染性胃肠炎病毒(TGEV)检测;同时采集109份血清和85份乳汁进行PEDV IgA抗体检测。结果显示:1—3月份10个猪场共有8 326头乳猪发生腹泻,死亡6 266头,死亡率为75.26%;病原检测PEDV阳性率为64.1%,TGEV阳性率为2.56%;血清中PEDV IgA抗体的阳性率为32.11%,乳汁中PEDV IgA抗体的阳性率为96.47%。病原检测结果表明,2016年春季山西省规模化种猪场乳猪腹泻的主要病原为PEDV,乳汁中PEDV IgA抗体水平与PEDV疫苗免疫效果或野毒感染呈正相关。
In the spring of 2016, part of piglets in Shanxi pig swine outbreaks of diarrhea. The clinical manifestations of diarrhea in 10 clinics in Taiyuan, Qixian, Jiexiu, Xiyang, Linfen, Yicheng, Lishi and Shuozhou in Shanxi Province were analyzed. The research on swine farms conducted statistical analysis on the death of suckling pigs, and collected the contents of 39 small intestine of diseased pigs for the detection of porcine epidemic diarrhea virus (PEDV) and swine transmissible gastroenteritis virus (TGEV) 109 serum samples and 85 milk samples were collected for PEDV IgA antibody detection. The results showed that a total of 8 326 suckling pigs in 10 pig farms in January-March had diarrhea with 6 266 deaths and the mortality rate was 75.26%. The positive rate of pathogen detection was 64.1% and the positive rate of TGEV was 2.56%. The serum PEDV The positive rate of IgA antibody was 32.11%, and the positive rate of PEDV IgA antibody in milk was 96.47%. Pathogen test results showed that the main pathogen of diarrhea in swine pigs in large-scale swine breeding farm in Shanxi Province in spring 2016 was PEDV, and the level of PEDV IgA antibody in milk was positively correlated with the immune effect or wild-type infection of PEDV vaccine.