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目的通过抗结核药物不良反应86例的临床资料分析,总结经验教训,为预防和处理肺结核治疗中出现的不良反应提供建议。方法对86例肺结核治疗中出现不良反应者详细病程记录、作相关检查以及追访记录,并给予相应的处理,处理包括住院及转科、暂停抗结核治疗、更改药物、延长疗程、对症处理、心理辅助、劳逸结合和饮食调理。结果肺结核治愈及完成疗程64例(74.4%),失访与拒治18例(20.9%),死亡4例(4.7%)。结论对抗结核药品不良反应既不能麻痹大意,掉以轻心,也不能有畏难情绪而轻易停药。
Objective To analyze the clinical data of 86 cases of adverse reactions of anti-tuberculosis drugs, summarize the experiences and lessons, and provide suggestions for preventing and treating the adverse reactions in the treatment of pulmonary tuberculosis. Methods A total of 86 cases of tuberculosis patients with adverse reactions were recorded in detail the course of the disease, related checks and follow-up records, and give appropriate treatment, including hospitalization and transfer of treatment, suspension of anti-TB treatment, change of drugs, prolonged treatment, symptomatic treatment, Psychological support, work and rest and diet conditioning. Results Tuberculosis was cured and completed in 64 cases (74.4%). There were 18 cases (20.9%) lost and refused treatment and 4 cases died (4.7%). Conclusion Adverse reactions to TB drugs can not be paralyzed, taken lightly, can not be afraid of emotions and easily discontinued.