齐墩果烷三萜类化合物具有广泛的生物活性,其中包括抗肿瘤活性。近年来的研究显示,该类化合物对肿瘤细胞的促凋亡作用与肿瘤细胞线粒体途径的激活密切相关。介绍了齐墩果烷三萜类化合物的抗肿瘤活性,以及该类化合物激活肿瘤细胞凋亡线粒体途径的机制,为进一步探究该类化合物的作用机制及相关药物研发提供参考。 Oleanane Triterpenoids have a wide range of biological activities, including anti-tumor activity. Recent studies have shown that the pro-apoptotic effect of these compounds on tumor cells is closely related to the activation of the mitochondrial pathway of tumor cells. The antitumor activity of oleanane triterpenoids and the mechanism of these compounds activating the mitochondrial pathway of tumor cells apoptosis are introduced, which may provide references for further exploring the mechanism of action of these compounds and the related drug development.