目的:了解我院精神科药物不良反应(ADR)发生情况,为临床安全用药提供参考。方法:对我院2010-2012年住院收集的精神科药品致ADR的报告进行分类统计和分析评价。结果:本次统计中精神科药品ADR的发生人群以男性居多,男女比例为1∶0.78。给药途径主要以口服给药。ADR以肝胆系统损害、中枢及外周神经系统损害、胃肠和皮肤及血液系统损害为主要的临床表现。结论:继续加强精神类药物的安全性监测,提高临床合理用药水平。 Objective: To understand the occurrence of psychiatric adverse drug reaction (ADR) in our hospital and provide references for clinical safety medication. Methods: The ADR reports of psychiatric drugs collected in our hospital from 2010 to 2012 were classified and analyzed. Results: In this survey, the incidence of ADR in psychiatric drugs was mostly male, with a male to female ratio of 1: 0.78. The route of administration is mainly oral. ADR to liver and gallbladder system damage, central and peripheral nervous system damage, gastrointestinal and skin and blood system damage as the main clinical manifestations. Conclusion: Continue to strengthen the safety monitoring of psychotropic substances and improve the clinical rational use of drugs.