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目的:分析药源性过敏性休克的基本情况及其发生原因。方法:对1991～1999年国内24种杂志进行专题检索。结果:共收集到487例药源性过敏性休克病例,由109种药物引起,发生率最高的药物为抗生素。死亡69例,65％患者(317例)在用药后5min内发生。文中还对药物性休克发生原因进行了讨论。结论:本文供临床参考,以减少药源性休克发生和死亡。
Objective: To analyze the basic situation and causes of drug-induced atopic shock. Methods: Thematic searches of 24 domestic magazines from 1991 to 1999 were conducted. Results: A total of 487 cases of drug-induced allergic shock were collected, caused by 109 drugs, the highest incidence of antibiotics. 69 patients died, 65% (317 patients) occurred within 5min after treatment. The article also discussed the causes of drug-induced shock. Conclusion: This article is for clinical reference to reduce the occurrence and death of drug-induced shock.