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目的探讨卵黄囊瘤的64层CT表现特征及病理学基础,提高对其诊断及鉴别诊断水平。资料与方法回顾性分析经手术及穿刺病理证实的9例卵黄囊瘤的临床特征及CT表现,并与病理对照研究。结果肿瘤位于纵隔3例,卵巢4例,盆腔隐睾1例,阴道1例。CT表现为圆形或卵圆形巨大肿块,以囊实性为主,内见大小不等的囊变区,增强扫描明显不均匀强化,实性为主者其内可见条状血管影。肿瘤病理学表现为间质排列成疏松的空网状结构,内见大量的瘤细胞,S-D小体等,8例治疗前检查血清甲胎蛋白(AFP)显著升高,均>1000μg/L,其中6例>3000μg/L。结论 64层CT增强扫描及多平面重组(MPR)能够清楚显示卵黄囊瘤形态、部位、大小及强化特征,结合血清AFP及年龄等临床资料,有利于其诊断和鉴别诊断。
Objective To investigate the 64-slice CT features and pathology of yolk sac tumor and to improve its diagnostic and differential diagnosis. Materials and Methods The clinical features and CT findings of 9 cases of yolk sac tumor confirmed by operation and biopsy were analyzed retrospectively. Results The tumor was located in 3 cases of mediastinum, 4 cases of ovary, 1 case of pelvic cryptorchidism and 1 case of vagina. CT showed a round or oval-shaped huge mass, with cystic solid-based, see within the cystic area of varying sizes, enhanced scanning was significantly enhanced, solid-based within the visible stripe vascular shadow. The tumor pathology was interstitial arranged in a loose empty network structure, see a large number of tumor cells, SD bodies, 8 cases of pretreatment serum alpha-fetoprotein (AFP) was significantly elevated, were> 1000μg / L, Of which 6 cases> 3000μg / L. Conclusion 64-slice CT and MPR can clearly show the morphology, location, size and enhancement of yolk sac tumor. Combined with clinical data such as serum AFP and age, it is helpful for the diagnosis and differential diagnosis of yolk sac tumor.