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于１９９１年测定了鼻咽癌（ＮＰＣ）和喉癌（ＬＣ）患者血清唾液酸（ＳＡ）和５种急相蛋白（ＡＰＰｓ），其中包括前清蛋白（ＰＡ），ａ＿１－抗胰蛋白酶（ａ＿１－ＡＴ），ａ＿１－酸性糖蛋白（ａ１－ＡＧＰ），触珠蛋白（ＨＰ）和转铁蛋白（ＴＦ），并将上述测定值组合入判别函数式，用于ＮＰＣ和ＬＣ的计算机辅助诊断和随访。本文为验证１９９１年报道的判别函数式，对２３８例未知诊断的初诊患者，双盲法检测血清ＳＡ、５ＡＰＰｓ和鼻咽组织活检及临床检查，结果发现：鼻咽癌的判别函数诊断与临床检查及活检结果符合率均在８０％以上。
Serum sialic acid (SA) and five acute phase proteins (APPs) were measured in patients with NPC and laryngeal cancer (LC) in 1991, including prealbumin (PA), a_1-antitrypsin -AT), a_1-acid glycoprotein (a1-AGP), haptoglobin (HP) and transferrin (TF), and the above measured values were combined into a discriminant function for computer-aided diagnosis of NPC and LC and Follow-up. In this paper, to verify the discriminant function formula reported in 1991, 238 cases of newly diagnosed patients with unknown diagnosis, double-blind detection of serum SA, 5APPs and nasopharyngeal tissue biopsy and clinical examination found that: the discriminant function of nasopharyngeal carcinoma diagnosis and clinical examination And biopsy results in line with the rate of more than 80%.