精神分裂症住院患者元认知训练疗效的随机对照研究

来源 :中华行为医学与脑科学杂志 | 被引量 : 0次 | 上传用户:jia_oracle
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目的 探讨元认知训练对精神分裂症患者临床症状、认知功能、自知力的短期影响和可操作性.方法 选取符合DSM-Ⅳ中精神分裂症标准的住院患者随机分配到研究组和对照组,各30例,分别接受四周共八次元认知训练和新闻讨论活动.采用阳性与阴性症状量表(PANSS)、精神分裂症认知功能评定量表(SCoRS)、自知力与治疗态度问卷(ITAQ)以及分珠任务在基线及四周后进行评定.结果 治疗后两组PANSS、SCoRS、ITAQ以及分珠任务的成绩均有显著改善(P<0.05),但研究组在阳性症状、认知功能及自知力[分别为(12.8±4.2)分,(31.7±13.9)分,(9.2±6.1)分]的改善情况明显优于对照组[分别为(15.6±5.9)分,(38.1±18.1)分,(5.5±5.8)分],差异有统计学意义(P<0.05).结论 元认知训练能够有效地改善精神分裂症患者的临床症状、认知功能及自知力.“,”Objective To explore the feasibility and efficiency of metacognitive training (MCT) in inpatients with schizophrenia,as well as the short-term effects of metacognitive training on symptoms,cognitive function,and insight.Methods Sixty inpatients that met the DSM-Ⅳ criteria for schizophrenia were randomly assigned to either MCT (research group,n =30) or an active controlled intervention (control group,n =30).Positive and Negative Syndrome Scale (PANSS),Schizophrenia Cognition Rating Scale (SCoRS),Insight and Treatment Attitude Questionnaire(ITAQ) and beads task are assessed at baseline and after completion of the training.Results After treatment,the scores of the two groups in PANSS,SCoRS,ITAQ and the bead task were significantly improved(P<0.05).The improvement of positive symptoms,cognitive function and insight in research group (12.8 ± 4.2,31.7 ± 13.9,9.2 ± 6.1 respectively) was significantly better than that in control group (15.6±5.9,38.1± 18.1,5.5±5.8 respectively),and the difference was statistically significant (P< 0.05).Conclusion Metacognitive training can effectively improve the clinical symptoms,cognitive function and insight for inpatients with schizophrenia.
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