作者近十年间行金属铂诱导化疗84例,其中顺铂+平阳霉素+长春新碱(PVP)组53例;卡铂+平阳霉素+长春新碱(CVP)组31例。治疗结果:PVP和CVP方案的近期疗效相接近,总有效率分别是86.79％和77.41％,两组差异无显著意义。毒副反应的比较表明:PVP以肾毒性、胃肠毒性和耳毒性为主,发生率分别为13.2％、79.24％和11.32％;而CVP则以骨髓毒性和肝毒性为特征,分别为38.70％和12.90％。两组分别出现的毒副反应及其并发症尚未影响诱导化疗的使用。 In the past ten years, 84 cases were treated with platinum induction chemotherapy, including 53 cases of cisplatin + pingyangmycin + vincristine (PVP) and 31 cases of carboplatin + pingyangmycin + vincristine (CVP). Treatment outcome: PVP and CVP programs near the immediate effect, the total effective rate was 86.79% and 77.41%, no significant difference between the two groups. The comparison of toxic and side effects showed that PVP was mainly nephrotoxicity, gastrointestinal toxicity and ototoxicity, the incidence rates were 13.2%, 79.24% and 11.32%, respectively. CVP was characterized by myelotoxicity and hepatotoxicity, which were 38.70% And 12.90%. Side effects of the two groups and their complications have not affected the use of induction chemotherapy.