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目的探讨新生儿低血糖症的临床表现及相关高危因素。方法对2009年1月至2010年7月我院新生儿科住院的新生儿低血糖症患儿与同期产科分娩的血糖正常对照组新生儿临床资料进行回顾性分析,对相关危险因素采用单因素及多因素回归分析。结果新生儿低血糖症267例,占同期住院新生儿的11.5%(267/2325),267例低血糖症中无症状者169例(63.3%),有症状者98例(36.7%),表现为吸吮无力72例(27.0%),震颤60例(22.5%),嗜睡40例(15.0%),尖叫22例(8.2%),发绀12例(4.9%),抽搐10例(3.8%)。Logistic多因素回归分析显示,低体温(OR=13.372)、早产儿(OR=13.451)、低出生体重儿(OR=4.489)、喂养不当(OR=42.378)、孕母糖尿病(OR=6.329)是新生儿发生低血糖的主要危险因素。结论对有低血糖高危因素的新生儿应常规监测血糖,及时采取措施纠正低血糖,以减少新生儿低血糖的发生。
Objective To investigate the clinical manifestations and related risk factors of neonatal hypoglycemia. Methods The clinical data of neonates with neonatal hypoglycemia hospitalized in neonatology department of our hospital from January 2009 to July 2010 were compared with neonates with normal glucose control group of obstetric delivery in the same period. The related risk factors were analyzed by single factor and Multi-factor regression analysis. Results 267 cases of neonatal hypoglycemia, accounting for 11.5% (267/2325) of newborns hospitalized in the same period, 169 cases (63.3%) of 267 cases of hypoglycemia asymptomatic, 98 cases (36.7%) of symptomatic There were 72 cases (27.0%) of sucking weakness, 60 cases (22.5%) of tremor, 40 (15.0%) of lethargy, 22 cases of screaming (8.2%), 12 cases of cyanosis (4.9% . Logistic multivariate regression analysis showed that hypoglycemia (OR = 13.372), premature infants (OR = 13.451), low birth weight infants (OR = 4.489), improper feeding (OR = 42.378) The main risk factors for hypoglycemia in newborns. Conclusion Neonates with high risk factors for hypoglycemia should routinely monitor blood glucose and promptly take measures to correct hypoglycemia to reduce neonatal hypoglycemia.