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目的探讨研究丙型、乙型肝炎病毒感染及甲胎球蛋白与肝癌的关系。方法乙肝标志物检测、丙肝抗体、AFP检测并进行比较。结果原发性肝癌患者肝炎病毒标志物检测:168例肝癌患者中HBsAg阳性125例(74.4%),抗-HCV阳性12例(7.14%);HBsAg及抗-HCV均阳性10例。HBsAg和(或)抗-HCV阳性137例。酒精性15例占8.92%;其他原因11例6.54%。抗-HCV在HBsAg阳性患者中所占比例8%,在HBsAg阴性患者中所占比例7.69%。结论HBV者发生HCV重叠感染时增加发生HCC的危险性。是由于在发生过程中和具有协同作用,促进肝细胞转化,更易发展为慢性肝炎和肝硬变,从而增加了肝细胞恶变。进一步做好乙肝和丙肝的防治工作,对控制发生有重要意义。
Objective To investigate the relationship between hepatitis C virus (C) and hepatitis B virus (A) Methods Hepatitis B markers, Hepatitis C antibody and AFP were detected and compared. Results Hepatitis virus markers were detected in primary hepatocellular carcinoma patients: 125 cases (74.4%) were positive for HBsAg, 12 cases (7.14%) were positive for anti-HCV, and 10 cases were positive for HBsAg and anti-HCV. 137 cases of HBsAg and / or anti-HCV positive. Alcohol 15 cases accounted for 8.92%; other reasons 11 cases 6.54%. The proportion of anti-HCV in HBsAg-positive patients was 8% and in HBsAg-negative patients 7.69%. Conclusion The risk of developing HCC is increased in patients with overlapping HCV infection. Is due to the occurrence and synergies in the process, and promote the transformation of liver cells, and more likely to develop chronic hepatitis and cirrhosis, thereby increasing hepatocellular malignancy. Further prevention and treatment of hepatitis B and C are of great significance to the control.