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目的探讨唑来膦酸治疗老年性骨质疏松症的临床疗效。方法选取新疆生产建设兵团医院2011年10月—2013年10月收治的80例老年性骨质疏松症患者,采用随机数字表法将患者分为观察组与对照组,各40例。对照组采用钙尔奇D治疗,观察组在对照组的基础上加用唑来膦酸治疗。观察两组的治疗效果及骨密度(BMD)水平。结果治疗后,两组患者治疗效果比较,差异有统计学意义(P<0.05);治疗后观察组股骨颈BMD和腰椎BMD水平均高于对照组,差异有统计学意义(P<0.05)。结论加用唑来膦酸治疗老年性骨质疏松症的疗效显著,能够有效提升患者BMD水平。
Objective To investigate the clinical efficacy of zoledronic acid in the treatment of senile osteoporosis. Methods Eighty elderly patients with osteoporosis were selected from Xinjiang Production and Construction Corps Hospital from October 2011 to October 2013. The patients were divided into observation group and control group with 40 cases in each group by random number table. The control group was treated with Calcium D, and the observation group was treated with zoledronic acid on the basis of the control group. The therapeutic effect and bone mineral density (BMD) level of the two groups were observed. Results After treatment, the therapeutic effects of the two groups were statistically significant (P <0.05). The BMD of femoral neck and BMD of lumbar spine of the observation group were significantly higher than those of the control group after treatment (P <0.05). Conclusion The effect of zoledronic acid in the treatment of senile osteoporosis is significant, which can effectively improve the level of BMD in patients.