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目的探讨0岁~15岁儿童血清神经元特异性烯醇化酶(NSE)与性别、年龄的相关性,为临床儿童相关疾病的诊断提供更为准确的参考指标。方法用电化学发光法检测900例0岁~15岁健康儿童的血清NSE值;统计学分析各年龄阶段、性别之间血清NSE的差异。结果不同性别儿童血清NSE检测值之间差异无统计学意义(P>0.05)。不同年龄组儿童血清NSE之间比较,<1个月组血清NSE最高,为(29.33±13.08)mg/L;1个月~3岁组血清NSE为(22.47±7.90)mg/L;>3岁组最低,为(20.56±7.80)mg/L;3组差异有统计学意义(P<0.05)。结论儿童血清NSE与性别无关,但随年龄的增长呈下降趋势。
Objective To investigate the relationship between gender, age and serum neuron specific enolase (NSE) in children aged 0-15 years and provide a more accurate reference for the diagnosis of children with clinical diseases. Methods Serum NSE values of 900 healthy children aged 0-15 years were measured by electrochemiluminescence method. The differences of serum NSE between different sexes were statistically analyzed. Results There was no significant difference in serum NSE between different sexes (P> 0.05). Serum NSE was significantly higher in children younger than 1 month (29.33 ± 13.08 mg / L), serum NSE was (22.47 ± 7.90) mg / L in 1 month to 3 years and> 3 The lowest in the old group was (20.56 ± 7.80) mg / L, with significant difference in the three groups (P <0.05). Conclusion Children’s serum NSE has nothing to do with gender, but declines with age.