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目的 观察口服米索前列醇对宫颈扩张的疗效和术中出血量。方法 选择停经 40～ 60d ,自愿采用负压吸引术终止妊娠的健康妇女 ,随机分成二组 ,观察组 3 3例术前 1h口服米索前列醇 40 0 μg ,对照组 3 0例不施任何药物。观察宫颈扩张度和术中出血量。结果 两组宫颈扩张差异有非常显著性 (P <0 0 1) ,术中出血量差异有显著性 (P <0 0 5 )。结论 人工流产术前 1h口服米索前列醇 40 0 μg为方便、有效的软化宫颈的理想方法 ,可减少手术操作 ,减少术中出血量 ,值得临床推广使用。
Objective To observe the curative effect of oral misoprostol on cervical dilatation and intraoperative blood loss. Methods Forty to sixty days after menopause, healthy women who voluntarily adopted negative pressure suction to terminate pregnancy were randomly divided into two groups. The observation group received oral administration of 40 0 μg of misoprostol 1 h before operation and 30 of the control group did not receive any drug . Observation of cervical dilatation and intraoperative bleeding. Results The difference of cervical dilatation between the two groups was significant (P <0.01). There was significant difference between the two groups (P <0.05). Conclusion Oral administration of misoprostol 40 0 μg 1 h before induced abortion is a convenient and effective method to soften cervix. It can reduce the operation and reduce the intraoperative blood loss, which is worthy of clinical application.