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目的:观察中西医结合治疗冠心病心绞痛的临床疗效。方法:选取116例心血瘀阻型冠心病心绞痛患者,按照随机数表法分为对照组和观察组各58例,在控制各种并发症的基础上,对照组给予盐酸曲美他嗪片进行治疗,观察组给予盐酸曲美他嗪片联合益气活血化浊汤进行治疗,2组均连续治疗4周。记录2组患者心绞痛发作的次数、发作持续时间及硝酸甘油用量等,比较2组的临床疗效及不良反应发生情况等。结果:治疗后,观察组总有效率为94.8%,对照组总有效率为74.1%,2组总有效率比较,差异有统计学意义(P<0.05)。2组心绞痛发作次数、持续时间均有所改善,与治疗前比较,差异均有统计学意义(P<0.05);观察组改善程度优于对照组,2项指标比较,差异均有统计学意义(P<0.05)。2组硝酸甘油用量均较治疗前减少,差异均有统计学意义(P<0.05);观察组用量少于对照组,差异有统计学意义(P<0.05)。结论:在常规控制各种并发症的基础上,采用盐酸曲美他嗪片联合益气活血化浊汤对冠心病心绞痛患者进行治疗,取得了较好的临床效果,可更为有效地改善患者的临床症状,减少心绞痛发作次数、发作持续时间及硝酸甘油的用量,同时安全性亦较好。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of angina pectoris. Methods: One hundred and sixteen patients with heart blood stasis and type of angina pectoris were enrolled and divided into control group and observation group according to random number table method, 58 cases each. On the basis of controlling various complications, the control group was given trimetazidine hydrochloride tablets The patients in the treatment group and the observation group were treated with trimebutine hydrochloride tablets and Yiqi Huoxue Huazhuo Decoction. The two groups were treated continuously for 4 weeks. The number of episodes of angina pectoris, the duration of attack and the dosage of nitroglycerin in the two groups were recorded. The clinical efficacy and the incidence of adverse reactions in the two groups were compared. Results: After treatment, the total effective rate was 94.8% in the observation group and 74.1% in the control group. The total effective rate in the two groups was statistically significant (P <0.05). The number and duration of angina pectoris in both groups were improved, compared with before treatment, the differences were statistically significant (P <0.05); the improvement degree of the observation group was better than that of the control group, the two indexes were statistically significant (P <0.05). The amount of nitroglycerin in both groups decreased compared with that before treatment, the differences were statistically significant (P <0.05). The dosage of observation group was less than that of the control group (P <0.05). Conclusion: On the basis of conventional control of various complications, trimethoprim hydrochloride tablets combined with Yiqi Huoxue Huazhuo Decoction in patients with coronary heart disease and angina pectoris, and achieved good clinical results, patients can be more effectively improved Clinical symptoms, reduce the number of angina attacks, the duration of attack and the amount of nitroglycerin, while the safety is also better.