胰腺癌预后恶劣,主要原因是其具有早期即发生淋巴结转移和沿神经束膜扩散至胰外的生物学特征。其发病率却不断增加,30年来西方国家已上升7倍,成为肿瘤死亡的第3位,国内也从上世纪60年代的15位上升至90年代的第6位[1]。胰腺癌现已公认为癌中之王,成为21世纪医学的顽固堡垒[2]。 The poor prognosis of pancreatic cancer, mainly due to its early and immediate lymph node metastasis and spread along the perineurium biological characteristics of the pancreas. Its incidence has been increasing. Western countries have risen sevenfold in 30 years, making them the third leading cause of cancer deaths in China and the fifth in the country from 15 in the 1960s to the sixth in the 1990s. [1] Pancreatic cancer is now recognized as the king of cancer, a staunch fortress of medical science in the 21st century [2].