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糖尿病及甲状腺疾病均是常见的内分泌代谢性疾病,糖尿病患者合并甲状腺疾病的发病率较健康人群高4.8%~31.4%[1]。1型糖尿病(T1DM)患者易合并自身免疫性甲状腺疾病(AITD)的机制与二者享有共同的遗传易感基因HLADR3、CTLA4、PTPN22有关[2]。2型糖尿病(T2DM)患者甲状腺疾病发病风险增高的机制尚不清楚,可能与T2DM患者存在一定程度的免疫系统异常有关。亚临床甲状腺功能减退症(以下简称亚临床甲减)是最常见的甲状腺疾病,发病率为
Diabetes and thyroid diseases are common endocrine and metabolic diseases, diabetic patients with thyroid disease incidence was 4.8% to 31.4% higher than healthy people [1]. The mechanism of AITD in patients with type 1 diabetes mellitus (T1DM) is related to the common genetic susceptibility genes HLADR3, CTLA4 and PTPN22 [2]. The mechanism of an increased risk of thyroid disease in patients with type 2 diabetes mellitus (T2DM) is unclear and may be related to the presence of some degree of immune system abnormalities in T2DM patients. Subclinical hypothyroidism (hereinafter referred to as subclinical hypothyroidism) is the most common thyroid disease, the incidence was