白癜风是一种常见的获得性色素脱失性疾病,以皮肤黑素细胞功能丧失为特点,全球发病率为0.5%~2%。白癜风病因尚不明确,自身免疫被认为是其发病的核心机制。白癜风患者可伴发多种自身免疫性疾病如甲状腺疾病、斑秃、Ⅰ型糖尿病、恶性贫血、类风湿关节炎。其中,自身免疫性甲状腺疾病在白癜风患者中较为常见。有研究报道认为在白癜风患者中甲状腺疾病的发病率为 Vitiligo is a common acquired depigmentation disease characterized by loss of function of the skin’s melanocytes, with a global incidence of 0.5% to 2%. Etiology of vitiligo is not yet clear, autoimmunity is considered the core of its pathogenesis. Vitiligo patients may be associated with a variety of autoimmune diseases such as thyroid disease, alopecia areata, type I diabetes, pernicious anemia, rheumatoid arthritis. Among them, autoimmune thyroid disease is more common in patients with vitiligo. Some studies have reported that the incidence of thyroid disease in patients with vitiligo