蜜丸在中成药中是一个古老的传统剂型,目前在国内外仍广泛使用。长期以来,蜜丸染菌是一个严重的问题,为了保证药品质量,使之符合中央卫生部颁布的标准,以达到中药灭菌要求,我厂利用原有的合坨机,经过适当的改革,采用了湿热合坨灭菌法,进行试验研究,初步得到满意的结果,此法设备简单,工艺流程短,经济简便易行,适用于大、中、小中药厂的蜜丸灭菌。一、设备:湿热合坨灭菌混合机是由原混合机(型号 DH200-1)加夹套,并在机外增设一个滤 Honey pill is an ancient traditional dosage form in Chinese patent medicine and is still widely used at home and abroad. For a long time, the contamination of honey granules is a serious problem. To ensure the quality of medicines and make them meet the standards promulgated by the Ministry of Health to meet the sterilization requirements of Chinese medicines, our factory has used the original mashing machines and has undergone appropriate reforms. The method of moist heat and helium sterilization was used to carry out experimental research, and preliminary satisfactory results were obtained. This method is simple in equipment, short in process flow, and simple and economical. It is suitable for the sterilization of honey pills in large, medium and small Chinese medicine plants. I. Equipment: The hot and humid combined sterilizing mixer is jacketed by the original mixer (model DH200-1), and a filter is added outside the machine.