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近日一项研究表明,肿瘤细胞中相同的细胞凋亡抑制蛋白也可以表达在引起自身免疫疾病的细胞中。乔治华盛顿大学医学与科学院神经科主席医学博士Henry Kaminski,与来自罗斯威尔帕克癌症研究所的同事们在Kusner实验室针对这个项目一起进行合作研究。他们发现了生存素,这是一种细胞凋亡的抑制蛋白,生存素在患有重症肌无力的病人体内淋巴细胞的白细胞中表达,但不在正常的个体中表达。这种情况也发生在动物模型的案例中。重症肌无力是一种严重的肌肉疾病,这种疾病会导致病人非常
A recent study showed that the same apoptotic proteins in tumor cells can also be expressed in cells that cause autoimmune diseases. Henry Kaminski, MD, chairman of neurology at the George Washington University School of Medicine and School of Medicine, collaborated with colleagues from Roswell Parker Cancer Institute at the Kusner lab on the project. They found that survivin, an inhibitor of apoptosis, is expressed in leukocytes of lymphocytes in patients with myasthenia gravis but not in normal individuals. This situation also occurs in the case of animal models. Myasthenia gravis is a serious muscle disease that causes the patient to be very much