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目的探讨结节性甲状腺肿超声造影模式,分析伽马拟合时间-强度曲线在结节性甲状腺肿中的诊断价值。方法选择80例结节性甲状腺肿患者,其中男性47例,女性33例;年龄19~56岁,平均年龄38.70岁。采用Logiq E9彩色多普勒超声诊断仪行超声造影,回顾性分析其用伽马拟合时间-强度曲线,对瘤体达峰时间(TtoPk)、到达时间(ATM)、梯度(Grad)、曲线下面积(Area)及峰值强度各参数进行对比。结果肿块与周围正常甲状腺组织呈等增强53例(66.3%),无增强12例(15.0%),不均匀低增强10例(12.5%),高增强5例(6.3%)。TtoPk、ATM、Grad、Area与周围甲状腺组织相比,差异无统计学意义(P>0.05)。峰值强度与周围甲状腺组织相比,差异有统计学意义(P<0.05)。结论结节性甲状腺肿的造影模式呈现多样性,但等增强仍然是其主要增强模式,且结节内部造影峰值强度略高于周围正常组织。
Objective To explore the mode of ultrasound-guided nodular goiter and analyze the diagnostic value of time-intensity curve of gamma-ray in nodular goiter. Methods Eighty patients with nodular goiter were selected, including 47 males and 33 females. The patients were 19-56 years old with the mean age of 38.70 years. Logiq E9 color Doppler ultrasonography was used to perform contrast-enhanced ultrasound and retrospectively analyzed the time-intensity curves with gamma-ray fitting. The time to peak (TtoPk), time to arrival (ATM), gradient, curve Under the area (Area) and peak intensity of the parameters were compared. Results There were 53 cases (66.3%) with equal enhancement in the tumor and surrounding normal thyroid tissue, 12 cases without enhancement (15.0%), 10 cases (12.5%) with uneven low enhancement and 5 cases (6.3%) with high enhancement. The differences of TtoPk, ATM, Grad, Area and surrounding thyroid tissue were not statistically significant (P> 0.05). There was significant difference between peak intensity and surrounding thyroid tissue (P <0.05). Conclusion The pattern of nodular goiter shows diversity, but the enhancement is still the main mode of enhancement. The peak intensity of the internal nodules is slightly higher than that of the surrounding normal tissues.