目的　加深对磁共振成像钆喷酸葡胺对比剂不良反应的认识。方法　报道 3例钆喷酸葡胺对比剂不良反应 ,观察 1例重度不良反应及抢救经过 ;复习钆对比剂不良反应的相关文献。结果　钆喷酸葡胺对比剂有不良反应 ,我院发生率为 0 .2 0 6%。结论　钆喷酸葡胺对比剂不良反应发生率虽低 ,但在患者对医疗质量要求较高的今天也应引起足够的重视 Objective To deepen the understanding of adverse reactions of magnetic resonance imaging of gadopentetate dimeglumine contrast agent. Methods Three adverse reactions of gadopentetate dimeglumine contrast agent were reported. One case of severe adverse reactions and rescue procedures were observed. The related literature about adverse reactions of gadolinium contrast agent was reviewed. Results gadopentetate meglumine contrast agent adverse reactions, our hospital incidence was 0.220%. Conclusions The incidence of adverse reactions of gadopentetate meglumine contrast agent is low, but enough attention should be paid to patients with high medical quality requirements today