By processing and analyzing geodetic data of vertical deformation, fault deformation and horizontal deformation by GPS in Gansu Ningxia Qinghai area and by comparing them with geological structures and many medium to strong earthquake activities in this area, some features of recent tectonic deformation anomaly and the development of medium to strong earthquakes are studied. The results show that: ①Near the main faults tectonic deformations are relatively large. The amount of vertical movement and the deformation status evolve with time. The horizontal movement and deformation show obvious compressional strike slip character. ②The dominant stress of tectonic deformation and seismic development in this area comes from the persistent northeastward compression of Qinghai Tibet block;The time spatial distribution evolution of tectonic deformation and seismic activities are closely related to dynamic evolution of block motion and regional tectonic stress field. ③The abnormal uplift and high gradient deformation belts and remarkable fault deformation anormaly on the borders of regional tectonic blocks are indicators of developing moderate to strong earthquakes but earthquakes may not necessarily take place in the position of maxium deformation, it usually occurred in the region where fault deformation anormaly shows “trend accumulation acceleration turn ” variation character or nearby. On the basis of above study, a preliminary prediction for strong earthquake risk in this area is given. By processing and analyzing geodetic data of vertical deformation, fault deformation and horizontal deformation by GPS in Gansu Ningxia Qinghai area and by comparing them with geological structures and many medium to strong earthquake activities in this area, some features of recent tectonic deformation anomaly and the development The medium of strong earthquakes are studied. The results show that: ①Near the main faults tectonic deformations are relatively large. The amount of vertical movement and the deformation status evolve with time. The horizontal movement and deformation show obvious compressional strike slip character. ②The dominant stress of tectonic deformation and seismic development in this area comes from the persistent northeastward compression of Qinghai Tibet block; The time spatial distribution evolution of tectonic deformation and seismic activities are closely related to dynamic evolution of block motion and regional tectonic stress field. ft and high gradient deformation belts and remarkable fault deformation anormaly on the borders said regional tectonic blocks are indicators of developing moderate to strong earthquakes but earthquakes may not necessarily take place in the position of maxium deformation, it nor occurred in the region where fault deformation an ormaly shows “trend accumulation acceleration turn” variation character or nearby. On the basis of above study, a preliminary prediction for strong earthquake risk in this area is given.