大量资料表明,在脑和脊髓内,内源性阿片样物质(OLS)和P物质的含量很高,它们在痛觉的调节中起着重要作用。但以往应用阿片受体阻断剂纳络酮进行实验,不能区分OLS中哪一具体组分起什么作用。本工作将抗脑啡肽抗血清IgG(ENK AS IgG)、抗β-内啡肽抗血清IgG(β-EP AS IgG)、抗P Numerous data indicate that the content of endogenous opioids (OLS) and substance P are very high in the brain and spinal cord and play an important role in the regulation of pain. In the past, however, experiments with naloxone, an opioid receptor blocker, failed to differentiate which one of the specific components of OLS plays its role. This work will enkephalin antiserum IgG (ENK AS IgG), anti-β-endorphin antiserum IgG (β-EP AS IgG), anti-P