重叠综合征为慢性阻塞性肺疾病 (COPD)与阻塞性睡眠呼吸暂停综合征 (OSAS)同时并存的疾病 ,其夜间低氧血症或高碳酸血症较单一疾病时更严重 ,易出现心肺并发症 ,常有严重的呼吸衰竭和肺动脉高压 ,临床表现重 ,进展快 ,治疗困难 ,此时仅治疗COPD得不到满意疗效 ,无法纠正呼吸衰 Overlap syndrome is a disease coexisting with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome (OSAS). Its nocturnal hypoxemia or hypercapnia is more serious than single disease and prone to cardiopulmonary complications Symptoms, often severe respiratory failure and pulmonary hypertension, clinical manifestations, rapid progress, treatment difficulties, this time only the treatment of COPD was not satisfactory results, can not correct respiratory failure