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中成药万年青甙膜是以高分子的聚乙烯为基质,将万年青强心甙加在其中,通过涂膜机制得薄膜。它具有工艺简单,含量均匀,容易实现联动化生产和无菌操作,生产时无粉尘飞扬等特点,且疗效可靠,服用方便,是临床应用中颇受欢迎的一种新剂型。我们在试制时,学习了上海医药工业研究院制造和使用药膜涂膜机的经验,作了部分改进,现将我们试制的一台药膜涂膜机,简介如下:一、原理:按工艺要求将万年青强心甙加入聚乙烯醇溶液中,将该溶液静置12小时除去泡沫。把药——聚乙烯醇溶液通过流涎咀,流到转动的不锈钢带上,经逆向热风干燥,除去溶剂(水)即得干燥药膜,再由卷膜盘将其卷集,经含量测定后,分剂量包装。
Chinese patent medicine Evergreen decidua is based on polymer polyethylene as the base, adding Evergreen’s core strength to it, through the coating mechanism to obtain the film. It has the advantages of simple process, uniform content, easy to realize linkage production and aseptic operation, no dust flying during production, etc., and it has reliable curative effect and is convenient to take. It is a popular new dosage form in clinical application. During the trial production, we learned the experience of the Shanghai Pharmaceutical Industry Research Institute to manufacture and use the coating film coating machine, and made some improvements. Now we have a trial of a coating film coating machine, the introduction is as follows: First, the principle: according to the process It is required that permanganate is added to the polyvinyl alcohol solution, and the solution is allowed to stand for 12 hours to remove the foam. The medicine-polyvinyl alcohol solution is passed through the flow nozzle and flows onto the rotating stainless steel belt. After drying in the reverse hot air, the solvent (water) is removed to obtain a dried film. The film is then wrapped by the film roll and the content is determined. , divided dose packaging.