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心律平(Propafenone,Rytmonorm)是一种具有局部麻醉作用、能直接抑制心肌细胞膜的新的高效抗心律失常药。于1975年由西德合成并用于临床。属IA类药。药理作用:对心肌细胞膜有直接稳定作用,具有降低单项动作电位最大上升速率及轻度延长动作电位时间和有效不应期的电生理作用,能延长窦房结、房室结的不应期,并可提高心肌细胞阈电位,明显地降低心肌自律性和中止折返,其作用较其它
Propafenone (Rytmonorm) is a new and highly effective antiarrhythmic drug with local anesthesia and direct inhibition of myocardial cell membrane. In 1975 by West Germany synthesis and clinical use. Is a class IA medicine. Pharmacological effects: the myocardial cell membrane has a direct stabilizing effect, with a single action potential to reduce the maximum rate of increase and mild prolongation of action potential time and effective refractory period of electrophysiological effects, can extend the sinoatrial node, atrioventricular node refractory period, And can increase the threshold potential of myocardial cells, significantly reduce myocardial self-discipline and termination of reentry, and its role than other