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目的评价采用10 F国产球囊导管经皮扩张成形术治疗体重≥10 kg儿童先天性肺动脉瓣狭窄的安全性及有效性。方法 2009年5月至2014年6月,在阜外心血管病医院实施经皮肺动脉瓣球囊成形术(PBPV)患者83例,年龄1~12(4.5±2.8)岁,体重10~60(20.3±9.4)kg。对其适应证、操作技术、导管资料、并发症及超声心动图测量跨肺动脉瓣收缩压差和肺动脉瓣反流情况进行分析。44例术后随访6~44个月。结果技术成功率100%,术后跨肺动脉瓣收缩压由(67.7±26.2)mmHg(1 mmHg=0.133 kPa)下降至(15.4±11.6)mmHg(P<0.01)。2例(2.4%)发生右心室流出道激惹,术后6个月均缓解,未见严重肺动脉瓣反流、三尖瓣损伤及再次介入治疗患者。结论采用10 F国产球囊导管介入治疗体重≥10 kg儿童先天性肺动脉瓣狭窄是安全有效的。
Objective To evaluate the safety and efficacy of 10F homemade balloon catheter percutaneous dilation in the treatment of congenital pulmonary valve stenosis in children weighing> 10 kg. Methods From May 2009 to June 2014, 83 patients with percutaneous pulmonary valve balloon angioplasty (PBPV) were enrolled in the Fu Wai Hospital of Cardiovascular Diseases, aged from 1 to 12 (4.5 ± 2.8) years and weighing from 10 to 60 ( 20.3 ± 9.4) kg. Analysis of indications, operative techniques, catheter data, complications, and echocardiographic measurements of systolic pressure across the pulmonary valve and pulmonary valve regurgitation. Forty-four patients were followed up for 6 to 44 months. Results The technical success rate was 100%. The systolic pressure across the pulmonary valve decreased from (67.7 ± 26.2) mmHg (1 mmHg = 0.133 kPa) to (15.4 ± 11.6) mmHg after operation (P <0.01). Right ventricular outflow tract irritation occurred in 2 cases (2.4%) and was relieved at 6 months after operation. There was no serious pulmonary valve regurgitation, tricuspid valve injury and interventional treatment again. Conclusion It is safe and effective to use 10 F homemade balloon catheter to treat congenital pulmonary valve stenosis in children weighing> 10 kg.