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目的 血尿的定位对诊断和治疗均有重要意义 ,该文通过测定尿α2 巨球蛋白 (α2 MG)的含量来区分肾小球性及非肾小球性血尿。方法 采用双夹心酶免疫测定法 (ELISA法 )测定 18例正常对照组 (A组 )、2 1例非肾小球性血尿 (B组 )及 2 3例肾小球性血尿 (C组 )的尿α2 MG的含量。结果 B组尿α2 MG 0 .2 12±0 .132mg/L 明显高于A组 0 .0 17± 0 .0 16mg/L 和C组 0 .0 2 4± 0 .0 15mg/L,差异均有显著性 (P <0 .0 1) ,而A ,C两组间差异无显著性 (P >0 .0 5 )。结论 尿α2 MG可作为区分肾小球性与非肾小球性血尿的有效指标。
Purpose Hematuria localization is of great importance in the diagnosis and treatment of glomerular and non-glomerular hematuria by measuring urinary α2 macroglobulin (α2 MG) content. Methods 18 cases of normal control group (group A), 21 cases of non-glomerular hematuria (group B) and 23 cases of glomerular hematuria (group C) were determined by double enzyme-linked immunosorbent assay (ELISA) Urine α2 MG content. Results Urinary α2 MG 0 .2 12 ± 0.132mg / L in group B was significantly higher than that in group A (0.017 ± 0.016mg / L) and group C (0.022 ± 0.015mg / L) (P <0.01). There was no significant difference between A and C groups (P> 0.05). Conclusion Urinary α2 MG can be used as an effective index to distinguish between glomerular and non-glomerular hematuria.