血液系统肿瘤疾病的诊断分型经历了以形态学为主的FAB分型,过渡到MIC分型,最终形成WHO分型。WHO《造血与淋巴组织肿瘤病理学和遗传学》采用了形态学(细胞学、病理学)、免疫表型、遗传学特点、分子生物学、临床表现和影像学技术,对每一类型血液系统肿瘤进行综合诊断分型[1-2],其分型更加精细准确。上述所包含的各项检查均构成WHO诊断分型标准的一个方面,许多 Diagnostic typing of hematological malignancies underwent morphological FAB typing, transition to MIC typing, and finally WHO typing. WHO “Hematopoietic and Lymphatic Tumor Pathology and Genetics” uses morphological (cytology, pathology), immunophenotyping, genetic characteristics, molecular biology, clinical presentation, and imaging techniques for each type of hematological system Tumor diagnosis of typing [1-2], its classification is more precise and accurate. Each of the above examinations constitutes one aspect of the WHO diagnostic typing criteria, many of them